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[personal profile] alias_sqbr
I am having to stop myself evangelising PEA to everyone I know with chronic pain, because I know how annoying that can be. But I am glad a friend told me about it, and it may be helpful for someone out there. So I'm going to put the info under a cut and you can read or not!

Palmitoylethanolamide or "PEA" is an over the counter pain reliever for chronic inflammatory pain. It has no serious side effects or contraindications, even for people who have problems with NSAIDs.

Upsides:
Studies show it is twice as effective as ibuprofen for neuropathic pain
No significant side effects
Reduces inflammation but doesn't have the negative effects of steroids or NSAIDs
No prescription required
Can be taken simultaneously with other medication, including other painkillers
Has been used safely for decades

The downsides:
It doesn't work for everyone.
It's kind of expensive, costing at least a dollar or two a day.
It can cause mild digestive issues in some people
It can take up to a few months to fully kick in

I am super happy with it for the pain caused by my Chronic Fatigue Syndrome/Systemic Exercise Intolerance Disease. My daily pain is down significantly with no side effects except very slightly worse reflux. When I have breakthrough pain opening a capsule onto my tongue works fairly well though that sets off my reflux a moderate amount. (note: my reflux is especially sensitive, ymmv) It started working within a few days.

Some general notes:

My understanding is that it's a chemical the body naturally produces but can get low on, which causes pain. It's thus more effective for systemic "the body thinks it's sick when it isn't" stuff like arthritis or fibromyalgia and less helpful for acute physical injury. But I have a friend with fibro it hasn't made a huge difference for, it's definitely very variable.

I bought mine for $110 delivery for 300 tablets from Fremantle Compounding Chemist. Apparently Bayswater 777 has it a little cheaper. You may have to ask your chemist to order it in, or order it online yourself.

I take 3 tablets a day, the suggested minimum dose is 2 and the maximum 16. I take two in the morning and one at night with food.

I asked my GP's advice and he'd never heard of it but said it sounded worth a shot. As far as I can tell it's not well known except by pain specialists but is gaining popularity.

Note: my information is for Perth, Western Australia. As far as I can tell the situation tends to be similar elsewhere but I can't say for sure. Also this is just intended as a brief intro to help people figure out if they want to research more thoroughly for themselves, I am Not That Kind Of Doctor.

Date: 2018-03-15 05:44 pm (UTC)
rachelmanija: (Default)
From: [personal profile] rachelmanija
Thank you very much! I never heard of it but I think I'll give it a try. It's available on Amazon.

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