Hmm, it's definitely something that imho, is worth testing? Generic meds have to use the same active ingredient, but they can all use different excipients and some of those can cause issues. For example my Nizatidine by the brand causes me no issues, but I get pretty nasty sporadic reflux with the generic, which is hilarious to me, because it's a reflux med. I have to insist on the 'real thing' because the excipients and potentially the shape of the capsule really mess with me and make it kind of useless for what it's meant to be helping with.
If you're getting the same kinds of side effects to three different families of blood pressure meds which can all cause slightly different constellations of side effects, it could be a reaction to the excipients / binders rather than the drug/s themselves? It's possible that Apotex uses similar excipients or all its blood pressure meds.
Is it possible to ask for samples from your GP the next time you see them? Maybe enough for two weeks or three weeks? I don't know what samples they have, but this could be a way to trial it as a theory.
I'm fine with some generic meds and others are like 'you won't even label if there's lactose in this capsule, which is *annoying.*' Like, I think one of the reasons I have issues with PEA is more to do with the capsule composition and less to do with the actual PEA. Some compounding chemists list the ingredients of their capsules, others don't. Generics don't list the name of their binders/inactives *at all.* Frustrating D:
Tbh this wouldn't be the first kind of rare-ish thing that has impacted you? I'm team 'try and if it fails at least you know'
![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)
zvi
no subject
Date: 2023-10-06 05:01 am (UTC)If you're getting the same kinds of side effects to three different families of blood pressure meds which can all cause slightly different constellations of side effects, it could be a reaction to the excipients / binders rather than the drug/s themselves? It's possible that Apotex uses similar excipients or all its blood pressure meds.
Is it possible to ask for samples from your GP the next time you see them? Maybe enough for two weeks or three weeks? I don't know what samples they have, but this could be a way to trial it as a theory.
I'm fine with some generic meds and others are like 'you won't even label if there's lactose in this capsule, which is *annoying.*' Like, I think one of the reasons I have issues with PEA is more to do with the capsule composition and less to do with the actual PEA. Some compounding chemists list the ingredients of their capsules, others don't. Generics don't list the name of their binders/inactives *at all.* Frustrating D:
Tbh this wouldn't be the first kind of rare-ish thing that has impacted you? I'm team 'try and if it fails at least you know'
Also this is 4 years old but I thought this removal of approval of 31 meds by the FDA due to poor manufacturing processes, including blood pressure meds in 2019 was interesting. Like, it could be a specific Apotex issue.